Coinbase’s Bitcoin premium index monitors the variance in BTC’s price between Coinbase Pro and Binance. For U.S. investors, particularly institutions, Coinbase emerges as the predominant choice due to its status as the largest and most liquid exchange in the region. Consequently, the majority of transactions take place on Coinbase. When demand surges on Coinbase, the price gap between Binance and Coinbase widens. Conversely, when demand is low, this gap narrows, signaling diminished interest. In contrast, Binance caters to a vast and diverse global customer base.